Almost everyone who takes the chickenpox vaccine is protected against contracting the disease. Because the varicella-zoster virus causes chickenpox, it is also known as the varicella vaccination. The virus used to create the vaccine is still alive but has been attenuated. Attenuated viruses are less virulent than unattenuated viruses. Even if the virus in the chickenpox vaccine is typically incapable of spreading disease, the body's immune system is nevertheless activated by it. Anyone who has had a chickenpox vaccination develops immunity to the illness as a result of that response. Infants, older individuals, and those with compromised immune systems are most at risk for serious, life-threatening consequences. But nobody can be certain who will experience severe consequences; anyone could. Getting a chickenpox vaccination has even another benefit. Without the vaccine, the sickness can be transferred through sneezing, coughing, or direct touch and is extremely contagious.

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